Dsc Orthologs Are Required for Hypoxia Adaptation, Triazole Drug Responses, and Fungal Virulence in Aspergillus fumigatus

Hypoxia is an environmental stress encountered by Aspergillus fumigatus during invasive pulmonary aspergillosis (IPA). The ability of this mold to adapt to hypoxia is important for fungal virulence and genetically regulated in part by the sterol regulatory element binding protein (SREBP) SrbA. SrbA...

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Main Authors: Willger, Sven D., Cornish, E. Jean, Chung, Dawoon, Fleming, Brittany A., Lehmann, Margaret M., Puttikamonkul, Srisombat, Cramer, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536281/
https://ncbi.nlm.nih.gov/pubmed/23104569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00252-12
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