Aspergillus fumigatus mitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses, and fungal pathogenesis

We previously observed that hypoxia is an important component of host microenvironments during pulmonary fungal infections. However, mechanisms of fungal growth in these in vivo hypoxic conditions are poorly understood. Here, we report that mitochondrial respiration is active in hypoxia (1% oxygen)...

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Bibliographic Details
Main Authors: Grahl, Nora, Dinamarco, Taisa Magnani, Willger, Sven D., Goldman, Gustavo H., Cramer, Robert A.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323727/
https://ncbi.nlm.nih.gov/pubmed/22443190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08034.x
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