SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

Sterol regulatory element binding proteins (SREBPs) are a class of basic helix-loop-helix transcription factors that regulate diverse cellular responses in eukaryotes. Adding to the recognized importance of SREBPs in human health, SREBPs in the human fungal pathogens Cryptococcus neoformans and Aspe...

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Detalhes bibliográficos
Main Authors: Blatzer, Michael, Barker, Bridget M., Willger, Sven D., Beckmann, Nicola, Blosser, Sara J., Cornish, Elizabeth J., Mazurie, Aurelien, Grahl, Nora, Haas, Hubertus, Cramer, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228822/
https://ncbi.nlm.nih.gov/pubmed/22144905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002374
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