Mechanism-Based Model of Parasite Growth and Dihydroartemisinin Pharmacodynamics in Murine Malaria

Murine models are used to study erythrocytic stages of malaria infection, because parasite morphology and development are comparable to those in human malaria infections. Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) models for antimalarials are scarce, despite their potential to optimize...

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Detaylı Bibliyografya
Asıl Yazarlar: Patel, Kashyap, Batty, Kevin T., Moore, Brioni R., Gibbons, Peter L., Bulitta, Jürgen B., Kirkpatrick, Carl M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535964/
https://ncbi.nlm.nih.gov/pubmed/23147722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01463-12
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