Piperaquine Pharmacodynamics and Parasite Viability in a Murine Malaria Model

Piperaquine (PQ) is an important partner drug in antimalarial combination treatments, but the long half-life of PQ raises concerns about drug resistance. Our aim was to investigate the extended antimalarial effect of PQ in a study of drug efficacy, reinoculation outcomes, and parasite viability afte...

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Bibliographic Details
Main Authors: Moore, Brioni R., Ilett, Kenneth F., Page-Sharp, Madhu, Jago, Jeffrey D., Batty, Kevin T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704627/
https://ncbi.nlm.nih.gov/pubmed/19380600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00056-09
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