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Thymidine Analogues Suppress Autophagy and Adipogenesis in Cultured Adipocytes
Lipoatrophy in HIV patients can result from prolonged exposure to thymidine analogues. Mitochondrial toxicity leading to dysregulated adipogenesis and increased cell death has been proposed as a leading factor in the etiology of peripheral fat loss. We hypothesized that thymidine analogues interfere...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535951/ https://ncbi.nlm.nih.gov/pubmed/23147731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01560-12 |
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