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Steps to ensure accuracy in genotype and SNP calling from Illumina sequencing data

BACKGROUND: Accurate calling of SNPs and genotypes from next-generation sequencing data is an essential prerequisite for most human genetics studies. A number of computational steps are required or recommended when translating the raw sequencing data into the final calls. However, whether each step...

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Detalhes bibliográficos
Main Authors: Liu, Qi, Guo, Yan, Li, Jiang, Long, Jirong, Zhang, Bing, Shyr, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535703/
https://ncbi.nlm.nih.gov/pubmed/23281772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S8-S8
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