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Genotype and SNP calling from next-generation sequencing data

Meaningful analysis of next-generation sequencing (NGS) data, which are produced extensively by genetics and genomics studies, relies crucially on the accurate calling of SNPs and genotypes. Recently developed statistical methods both improve and quantify the considerable uncertainty associated with...

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Detalhes bibliográficos
Main Authors: Nielsen, Rasmus, Paul, Joshua S., Albrechtsen, Anders, Song, Yun S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593722/
https://ncbi.nlm.nih.gov/pubmed/21587300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2986
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