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Genotype and SNP calling from next-generation sequencing data

Meaningful analysis of next-generation sequencing (NGS) data, which are produced extensively by genetics and genomics studies, relies crucially on the accurate calling of SNPs and genotypes. Recently developed statistical methods both improve and quantify the considerable uncertainty associated with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nielsen, Rasmus, Paul, Joshua S., Albrechtsen, Anders, Song, Yun S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593722/
https://ncbi.nlm.nih.gov/pubmed/21587300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2986
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