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Cyclopentane-Peptide Nucleic Acids for Qualitative, Quantitative, and Repetitive Detection of Nucleic Acids

We report the development of chemically-modified peptide nucleic acids (PNAs) as probes for qualitative and quantitative detection of DNA. The remarkable stability of PNAs toward enzymatic degradation makes this class of molecules ideal to develop as part of a diagnostic device that can be used outs...

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Detalhes bibliográficos
Main Authors: Micklitsch, Christopher M., Oquare, Bereket Yemane, Zhao, Chao, Appella, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535555/
https://ncbi.nlm.nih.gov/pubmed/23214925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3026459
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