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How Promiscuous Are Pharmaceutically Relevant Compounds? A Data-Driven Assessment
Given the increasing notion of target promiscuity of bioactive compounds and polypharmacological drug behavior, a detailed analysis of publicly available compound activity data from medicinal chemistry sources was carried out to determine and quantify the degree of promiscuity of active compounds ac...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer US
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535109/ https://ncbi.nlm.nih.gov/pubmed/23090085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9421-y |
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