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Direct Identification of Nonreducing GlcNAc Residues on N-Glycans of Glycoproteins Using a Novel Chemoenzymatic Method

The mutant β1,4-galactosyltransferase (β4Gal-T1), β4Gal-T1-Y289L, in contrast to wild-type β4Gal-T1, can transfer GalNAc from the sugar donor UDP-GalNAc to the acceptor, GlcNAc, with efficiency as good as that of galactose from UDP-Gal. Furthermore, the mutant can also transfer a modified sugar, C2...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Boeggeman, Elizabeth, Ramakrishnan, Boopathy, Kilgore, Charlton, Khidekel, Nelly, Hsieh-Wilson, Linda C., Simpson, John T., Qasba, Pradman K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534963/
https://ncbi.nlm.nih.gov/pubmed/17370997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc060341n
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