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Role of glutamic acid decarboxylase 67 in regulating cortical parvalbumin and GABA membrane transporter 1 expression: Implications for schizophrenia

Markers of GABA neurotransmission are altered in multiple regions of the neocortex in individuals with schizophrenia. Lower levels of glutamic acid decarboxylase 67 (GAD67) mRNA and protein, which is responsible for most cortical GABA synthesis, are accompanied by lower levels of GABA membrane trans...

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Autors principals: Curley, Allison A., Eggan, Stephen M., Lazarus, Matt S., Huang, Z. Josh, Volk, David W., Lewis, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534919/
https://ncbi.nlm.nih.gov/pubmed/23103418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.10.018
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