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Cortical Deficits of Glutamic Acid Decarboxylase 67 Expression in Schizophrenia: Clinical, Protein, and Cell Type-Specific Features

OBJECTIVE: Cognitive deficits in schizophrenia are associated with altered activity of the dorsolateral prefrontal cortex, which has been attributed to lower expression of the 67 kDa isoform of glutamic acid decarboxylase (GAD67), the major γ-aminobutyric acid (GABA)-synthesizing enzyme. However, li...

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Detalhes bibliográficos
Main Authors: Curley, Allison A., Arion, Dominique, Volk, David W., Asafu-Adjei, Josephine K., Sampson, Allan R., Fish, Kenneth N., Lewis, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273780/
https://ncbi.nlm.nih.gov/pubmed/21632647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2011.11010052
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