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Markedly lower glutamic acid decarboxylase 67 protein levels in a subset of boutons in schizophrenia

BACKGROUND: Convergent findings indicate that cortical GABAergic circuitry is altered in schizophrenia. Postmortem studies have consistently found lower levels of GAD67 mRNA in the prefrontal cortex (PFC) of subjects with schizophrenia. At the cellular level, the density of GABA neurons with detecta...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Psychiatry
Main Authors: Rocco, Brad R., Lewis, David A., Fish, Kenneth N.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744808/
https://ncbi.nlm.nih.gov/pubmed/26364548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.07.022
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