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Markedly lower glutamic acid decarboxylase 67 protein levels in a subset of boutons in schizophrenia
BACKGROUND: Convergent findings indicate that cortical GABAergic circuitry is altered in schizophrenia. Postmortem studies have consistently found lower levels of GAD67 mRNA in the prefrontal cortex (PFC) of subjects with schizophrenia. At the cellular level, the density of GABA neurons with detecta...
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| Veröffentlicht in: | Biol Psychiatry |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4744808/ https://ncbi.nlm.nih.gov/pubmed/26364548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.07.022 |
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