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Recognizing uncertainty increases robustness and reproducibility of mass spectrometry-based protein inferences

Parsimony and protein grouping are widely employed to enforce economy in the number of identified proteins, with the goal of increasing the quality and reliability of protein identifications; however, in a counterintuitive manner, parsimony and protein grouping may actually decrease the reproducibil...

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書目詳細資料
Main Authors: Serang, Oliver, Moruz, Luminita, Hoopmann, Michael R., Käll, Lukas
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534833/
https://ncbi.nlm.nih.gov/pubmed/23148905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr300426s
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