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Optimization of Experimental Parameters in Data-Independent Mass Spectrometry Significantly Increases Depth and Reproducibility of Results

Comprehensive, reproducible and precise analysis of large sample cohorts is one of the key objectives of quantitative proteomics. Here, we present an implementation of data-independent acquisition using its parallel acquisition nature that surpasses the limitation of serial MS2 acquisition of data-d...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Bruderer, Roland, Bernhardt, Oliver M., Gandhi, Tejas, Xuan, Yue, Sondermann, Julia, Schmidt, Manuela, Gomez-Varela, David, Reiter, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724188/
https://ncbi.nlm.nih.gov/pubmed/29070702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000314
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