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Recognizing uncertainty increases robustness and reproducibility of mass spectrometry-based protein inferences
Parsimony and protein grouping are widely employed to enforce economy in the number of identified proteins, with the goal of increasing the quality and reliability of protein identifications; however, in a counterintuitive manner, parsimony and protein grouping may actually decrease the reproducibil...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534833/ https://ncbi.nlm.nih.gov/pubmed/23148905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr300426s |
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