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Faster Mass Spectrometry-based Protein Inference: Junction Trees are More Efficient than Sampling and Marginalization by Enumeration

The problem of identifying the proteins in a complex mixture using tandem mass spectrometry can be framed as an inference problem on a graph that connects peptides to proteins. Several existing protein identification methods make use of statistical inference methods for graphical models, including e...

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Detalhes bibliográficos
Main Authors: Serang, Oliver, Noble, William Stafford
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389307/
https://ncbi.nlm.nih.gov/pubmed/22331862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TCBB.2012.26
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