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Efficient marginalization to compute protein posterior probabilities from shotgun mass spectrometry data
The problem of identifying proteins from a shotgun proteomics experiment has not been definitively solved. Identifying the proteins in a sample requires ranking them, ideally with interpretable scores. In particular, “degenerate” peptides, which map to multiple proteins, have made such a ranking dif...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948606/ https://ncbi.nlm.nih.gov/pubmed/20712337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100594k |
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