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Learning score function parameters for improved spectrum identification in tandem mass spectrometry experiments

The identification of proteins from spectra derived from a tandem mass spectrometry experiment involves several challenges: matching each observed spectrum to a peptide sequence, ranking the resulting collection of peptide-spectrum matches, assigning statistical confidence estimates to the matches,...

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Detalhes bibliográficos
Main Authors: Spivak, Marina, Bereman, Michael S., MacCoss, Michael J., Noble, William Stafford
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436966/
https://ncbi.nlm.nih.gov/pubmed/22866926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr300234m
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