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Efficient marginalization to compute protein posterior probabilities from shotgun mass spectrometry data

The problem of identifying proteins from a shotgun proteomics experiment has not been definitively solved. Identifying the proteins in a sample requires ranking them, ideally with interpretable scores. In particular, “degenerate” peptides, which map to multiple proteins, have made such a ranking dif...

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Autors principals: Serang, Oliver, MacCoss, Michael J., Noble, William Stafford
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948606/
https://ncbi.nlm.nih.gov/pubmed/20712337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100594k
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