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Structural Constraints in Collaborative Competition of Transcription Factors Against the Nucleosome

Cooperativity in transcription factor (TF) binding is essential in eukaryotic gene regulation, and arises through diverse mechanisms. Here we focus on one mechanism, collaborative competition, which is of interest because it arises both automatically, with no requirement for TF co-evolution, and spo...

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Hlavní autoři: Moyle-Heyrman, Georgette, Tims, Hannah S., Widom, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534743/
https://ncbi.nlm.nih.gov/pubmed/21821044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.07.032
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