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Two-step Mechanism for Modifier of Transcription 1 (Mot1) Enzyme-catalyzed Displacement of TATA-binding Protein (TBP) from DNA

The TATA box binding protein (TBP) is a central component of the transcription preinitiation complex, and its occupancy at a promoter is correlated with transcription levels. The TBP-promoter DNA complex contains sharply bent DNA and its interaction lifetime is limited by the ATP-dependent TBP displ...

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Detalhes bibliográficos
Main Authors: Moyle-Heyrman, Georgette, Viswanathan, Ramya, Widom, Jonathan, Auble, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308732/
https://ncbi.nlm.nih.gov/pubmed/22298788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.333484
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