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Molecular Mechanism of Mot1, a TATA-binding Protein (TBP)-DNA Dissociating Enzyme

The essential Saccharomyces cerevisiae ATPase Mot1 globally regulates transcription by impacting the genomic distribution and activity of the TATA-binding protein (TBP). In vitro, Mot1 forms a ternary complex with TBP and DNA and can use ATP hydrolysis to dissociate the TBP-DNA complex. Prior work s...

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Pubblicato in:J Biol Chem
Autori principali: Viswanathan, Ramya, True, Jason D., Auble, David T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957054/
https://ncbi.nlm.nih.gov/pubmed/27255709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.730366
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