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Dynamics of Nucleosome Invasion by DNA Binding Proteins

Nucleosomes sterically occlude their wrapped DNA from interaction with many large protein complexes. How proteins gain access to nucleosomal DNA target sites in vivo is not known. Outer stretches of the nucleosomal DNA spontaneously unwrap and rewrap with high frequency, providing rapid and efficien...

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Bibliografiske detaljer
Main Authors: Tims, Hannah S., Gurunathan, Kaushik, Levitus, Marcia, Widom, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164294/
https://ncbi.nlm.nih.gov/pubmed/21669206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.05.044
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