PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer

The phosphatidylinositol 3′ kinase (PI3K) pathway is commonly activated in breast cancer and aberrations such as PI3K mutations are common. Recent exciting clinical trial results in advanced estrogen receptor-positive (ER) breast cancer support mTOR activation is a major means of estrogen-independen...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Loi, Sherene, Michiels, Stefan, Baselga, Jose, Bartlett, John M. S., Singhal, Sandeep K., Sabine, Vicky S., Sims, Andrew H., Sahmoud, Tarek, Dixon, J. Michael, Piccart, Martine J., Sotiriou, Christos
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534682/
https://ncbi.nlm.nih.gov/pubmed/23301057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053292
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky