DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

Using whole blood from 15 twin pairs discordant for breast cancer and high-resolution (450K) DNA methylation analysis, we identified 403 differentially methylated CpG sites including known and novel potential breast cancer genes. Confirming the results in an independent validation cohort of 21 twin...

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Detaylı Bibliyografya
Asıl Yazarlar: Heyn, Holger, Carmona, F. Javier, Gomez, Antonio, Ferreira, Humberto J., Bell, Jordana T., Sayols, Sergi, Ward, Kirsten, Stefansson, Olafur A., Moran, Sebastian, Sandoval, Juan, Eyfjord, Jorunn E., Spector, Tim D., Esteller, Manel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2013
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Original Manuscript
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534196/
https://ncbi.nlm.nih.gov/pubmed/23054610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs321
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