DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

Using whole blood from 15 twin pairs discordant for breast cancer and high-resolution (450K) DNA methylation analysis, we identified 403 differentially methylated CpG sites including known and novel potential breast cancer genes. Confirming the results in an independent validation cohort of 21 twin...

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Bibliografiske detaljer
Main Authors: Heyn, Holger, Carmona, F. Javier, Gomez, Antonio, Ferreira, Humberto J., Bell, Jordana T., Sayols, Sergi, Ward, Kirsten, Stefansson, Olafur A., Moran, Sebastian, Sandoval, Juan, Eyfjord, Jorunn E., Spector, Tim D., Esteller, Manel
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
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Original Manuscript
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534196/
https://ncbi.nlm.nih.gov/pubmed/23054610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs321
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