C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia

C/EBPs are a family of transcription factors that regulate growth control and differentiation of various tissues. We found that C/EBPγ is highly upregulated in a subset of acute myeloid leukemia (AML) samples characterized by C/EBPα hypermethylation/silencing. Similarly, C/EBPγ was upregulated in mu...

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Autors principals: Alberich-Jordà, Meritxell, Wouters, Bas, Balastik, Martin, Shapiro-Koss, Clara, Zhang, Hong, DiRuscio, Annalisa, Radomska, Hanna S., Ebralidze, Alexander K., Amabile, Giovanni, Ye, Min, Zhang, Junyan, Lowers, Irene, Avellino, Roberto, Melnick, Ari, Figueroa, Maria E., Valk, Peter J.M., Delwel, Ruud, Tenen, Daniel G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533560/
https://ncbi.nlm.nih.gov/pubmed/23160200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65102
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