Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension

Integrin-based focal adhesions (FA) transmit anchorage and traction forces between the cell and the extracellular matrix (ECM). To gain further insight into the physical parameters of the ECM that control FA assembly and force transduction in non-migrating cells, we used fibronectin (FN) nanopattern...

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Détails bibliographiques
Auteurs principaux: Coyer, Sean R., Singh, Ankur, Dumbauld, David W., Calderwood, David A., Craig, Susan W., Delamarche, Emmanuel, García, Andrés J.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533393/
https://ncbi.nlm.nih.gov/pubmed/22899715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.108035
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