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Transient frictional slip between integrin and the ECM in focal adhesions under myosin-II tension

BACKGROUND: The spatiotemporal regulation of adhesion to the extracellular matrix is important in metazoan cell migration and mechanosensation. While adhesion assembly depends on intracellular and extracellular tension, the biophysical regulation of force transmission between the actin cytoskeleton...

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Bibliographic Details
Main Authors: Aratyn-Schaus, Yvonne, Gardel, Margaret L.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902720/
https://ncbi.nlm.nih.gov/pubmed/20541412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.05.049
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