Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents

Lignende værker

• Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy
  af: Mallinson, Joanne E, et al.
  Udgivet: (2009)
• PPARδ and FOXO1 Mediate Palmitate-Induced Inhibition of Muscle Pyruvate Dehydrogenase Complex and CHO Oxidation, Events Reversed by Electrical Pulse Stimulation
  af: Hung-Che Chien, et al.
  Udgivet: (2020-08-01)
• PPARδ and FOXO1 Mediate Palmitate-Induced Inhibition of Muscle Pyruvate Dehydrogenase Complex and CHO Oxidation, Events Reversed by Electrical Pulse Stimulation
  af: Chien, Hung-Che, et al.
  Udgivet: (2020)
• Muscle pyruvate availability can limit the flux, but not activation, of the pyruvate dehydrogenase complex during submaximal exercise in humans
  af: Constantin-Teodosiu, Dumitru, et al.
  Udgivet: (2004)
• Regulation of Muscle Pyruvate Dehydrogenase Complex in Insulin Resistance: Effects of Exercise and Dichloroacetate
  af: Constantin-Teodosiu, Dumitru
  Udgivet: (2013)