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HACE1 Is a Tumor Suppressor Gene Candidate in Natural Killer Cell Neoplasms
HACE1 is an E3 ubiquitin ligase located in 6q21, the genomic region frequently deleted in natural killer (NK) cell malignancies. Here, we report HACE1 as a candidate tumor suppressor gene silenced through a combination of deletion and cytosine phosphate guanine island hypermethylation. We detected d...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Investigative Pathology
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532710/ https://ncbi.nlm.nih.gov/pubmed/23142381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.09.012 |
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