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PRDM1 is a tumor suppressor gene in natural killer cell malignancies
Natural killer cell lymphoma (NKCL) constitutes a rare and aggressive form of non-Hodgkin lymphoma, and there is little insight into its pathogenesis. Here we show that PRDM1 is a tumor suppressor gene in NKCLs that is inactivated by a combination of monoallelic deletion and promoter CpG island hype...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250125/ https://ncbi.nlm.nih.gov/pubmed/22143801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115128108 |
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