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Cardiomyocyte-specific deletion of leptin receptors causes lethal heart failure in Cre-recombinase-mediated cardiotoxicity

Although disruption of leptin signaling is associated with obesity as well as cardiac lipid accumulation and dysfunction, it has been difficult to separate the direct effects of leptin on the heart from those associated with the effects of leptin on body weight and fat mass. Using Cre-loxP recombina...

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Detalhes bibliográficos
Main Authors: Hall, Michael E., Smith, Grant, Hall, John E., Stec, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532590/
https://ncbi.nlm.nih.gov/pubmed/23115124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00292.2012
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