Shp2 signaling in POMC neurons is important for leptin's actions on blood pressure, energy balance, and glucose regulation

Previous studies showed that Src homology-2 tyrosine phosphatase (Shp2) is an important regulator of body weight. In this study, we examined the impact of Shp2 deficiency specifically in proopiomelanocortin (POMC) neurons on metabolic and cardiovascular function and on chronic blood pressure (BP) an...

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Detalles Bibliográficos
Publicado en:Am J Physiol Regul Integr Comp Physiol
Autores principales: do Carmo, Jussara M., da Silva, Alexandre A., Ebaady, Sabira E., Sessums, Price O., Abraham, Ralph S., Elmquist, Joel K., Lowell, Bradford B., Hall, John E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
Materias:
Obesity, Diabetes and Energy Homeostasis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269667/
https://ncbi.nlm.nih.gov/pubmed/25339680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00131.2014
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