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Sixteen years and counting: an update on leptin in energy balance

Cloned in 1994, the ob gene encodes the protein hormone leptin, which is produced and secreted by white adipose tissue. Since its discovery, leptin has been found to have profound effects on behavior, metabolic rate, endocrine axes, and glucose fluxes. Leptin deficiency in mice and humans causes mor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gautron, Laurent, Elmquist, Joel K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104762/
https://ncbi.nlm.nih.gov/pubmed/21633176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45888
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