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A three-state model of telomere control over human proliferative boundaries
Intrinsic limits on cellular proliferation in human somatic tissue serves as a tumor suppressor mechanism by restricting cell growth in aged cells with accrued pre-cancerous mutations. This is accompanied by the potential cost of restricting regenerative capacity and contributing to cellular and org...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532573/ https://ncbi.nlm.nih.gov/pubmed/22947495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2012.08.007 |
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