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Differential Targeting of Unpaired Bases within Duplex DNA by the Natural Compound Clerocidin: A Valuable Tool to Dissect DNA Secondary Structure

Non-canonical DNA structures have been postulated to mediate protein-nucleic acid interactions and to function as intermediates in the generation of frame-shift mutations when errors in DNA replication occur, which result in a variety of diseases and cancers. Compounds capable of binding to non-cano...

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Detalhes bibliográficos
Main Authors: Nadai, Matteo, Palù, Giorgio, Palumbo, Manlio, Richter, Sara N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532440/
https://ncbi.nlm.nih.gov/pubmed/23285245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052994
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