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Epigenetic Regulation of Galectin-3 Expression by β1 Integrins Promotes Cell Adhesion and Migration

Introduction of the integrin β1- but not the β3-subunit in GE11 cells induces an epithelial-to-mesenchymal-transition (EMT)-like phenomenon that is characterized by the loss of cell-cell contacts, cell scattering, increased cell migration and RhoA activity, and fibronectin fibrillogenesis. Because g...

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Autors principals: Margadant, Coert, van den Bout, Iman, van Boxtel, Antonius L., Thijssen, Victor L., Sonnenberg, Arnoud
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531783/
https://ncbi.nlm.nih.gov/pubmed/23118221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.426445
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