Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT(2A)·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function

Serotonin and glutamate G protein-coupled receptor (GPCR) neurotransmission affects cognition and perception in humans and rodents. GPCRs are capable of forming heteromeric complexes that differentially alter cell signaling, but the role of this structural arrangement in modulating behavior remains...

Full description

Saved in:
Bibliographic Details
Main Authors: Moreno, José L., Muguruza, Carolina, Umali, Adrienne, Mortillo, Steven, Holloway, Terrell, Pilar-Cuéllar, Fuencisla, Mocci, Giuseppe, Seto, Jeremy, Callado, Luis F., Neve, Rachael L., Milligan, Graeme, Sealfon, Stuart C., López-Giménez, Juan F., Meana, J. Javier, Benson, Deanna L., González-Maeso, Javier
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531745/
https://ncbi.nlm.nih.gov/pubmed/23129762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413161
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items