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Functional crosstalk and heteromerization of serotonin 5-HT(2A) and dopamine D(2) receptors

The serotonin 5-HT(2A) receptor (5-HT(2A)R) and dopamine D(2) receptor (D(2)R) are high-affinity G protein-coupled receptor targets for two different classes of antipsychotic drugs used to treat schizophrenia. Interestingly, the antipsychotic effects are not based on the regulation of same signaling...

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Main Authors: Albizu, Laura, Holloway, Terrell, González-Maeso, Javier, Sealfon, Stuart C.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556730/
https://ncbi.nlm.nih.gov/pubmed/21645528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.05.023
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