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Chronic treatment with LY341495 decreases 5-HT(2A) receptor binding and hallucinogenic effects of LSD in mice

Hallucinogenic drugs, such as lysergic acid diethylamide (LSD), mescaline and psilocybin, alter perception and cognitive processes. All hallucinogenic drugs have in common a high affinity for the serotonin 5-HT(2A) receptor. Metabotropic glutamate 2/3 (mGlu2/3) receptor ligands show efficacy in modu...

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Detalhes bibliográficos
Main Authors: Moreno, José L., Holloway, Terrell, Rayannavar, Vinayak, Sealfon, Stuart C., González-Maeso, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578056/
https://ncbi.nlm.nih.gov/pubmed/23333599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.12.053
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