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Chronic treatment with LY341495 decreases 5-HT(2A) receptor binding and hallucinogenic effects of LSD in mice

Hallucinogenic drugs, such as lysergic acid diethylamide (LSD), mescaline and psilocybin, alter perception and cognitive processes. All hallucinogenic drugs have in common a high affinity for the serotonin 5-HT(2A) receptor. Metabotropic glutamate 2/3 (mGlu2/3) receptor ligands show efficacy in modu...

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Autors principals: Moreno, José L., Holloway, Terrell, Rayannavar, Vinayak, Sealfon, Stuart C., González-Maeso, Javier
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578056/
https://ncbi.nlm.nih.gov/pubmed/23333599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.12.053
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