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Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT(2A)·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function

Serotonin and glutamate G protein-coupled receptor (GPCR) neurotransmission affects cognition and perception in humans and rodents. GPCRs are capable of forming heteromeric complexes that differentially alter cell signaling, but the role of this structural arrangement in modulating behavior remains...

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Bibliografische gegevens
Hoofdauteurs: Moreno, José L., Muguruza, Carolina, Umali, Adrienne, Mortillo, Steven, Holloway, Terrell, Pilar-Cuéllar, Fuencisla, Mocci, Giuseppe, Seto, Jeremy, Callado, Luis F., Neve, Rachael L., Milligan, Graeme, Sealfon, Stuart C., López-Giménez, Juan F., Meana, J. Javier, Benson, Deanna L., González-Maeso, Javier
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531745/
https://ncbi.nlm.nih.gov/pubmed/23129762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413161
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