Inhibition of coronavirus 229E replication by actinomycin D.

The yields of human coronavirus 229E grown in L132 cells were markedly inhibited by actinomycin D, the 50% inhibitory dose being 0.1 micron/ml. Inhibition was maximal during the early phase of virus replication, did not appear to involve viral RNA synthesis per se, and was shown to be dependent on t...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Kennedy, D A, Johnson-Lussenburg, C M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/430598/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.29.1.401-404.1979
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