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Inhibition of coronavirus 229E replication by actinomycin D.

The yields of human coronavirus 229E grown in L132 cells were markedly inhibited by actinomycin D, the 50% inhibitory dose being 0.1 micron/ml. Inhibition was maximal during the early phase of virus replication, did not appear to involve viral RNA synthesis per se, and was shown to be dependent on t...

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Detalhes bibliográficos
Main Authors: Kennedy, D A, Johnson-Lussenburg, C M
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC353142/
https://ncbi.nlm.nih.gov/pubmed/430598
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