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Inhibition of coronavirus 229E replication by actinomycin D.
The yields of human coronavirus 229E grown in L132 cells were markedly inhibited by actinomycin D, the 50% inhibitory dose being 0.1 micron/ml. Inhibition was maximal during the early phase of virus replication, did not appear to involve viral RNA synthesis per se, and was shown to be dependent on t...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1979
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC353142/ https://ncbi.nlm.nih.gov/pubmed/430598 |
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