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Two Sets of Paralogous Genes Encode the Enzymes Involved in the Early Stages of Clavulanic Acid and Clavam Metabolite Biosynthesis in Streptomyces clavuligerus

Recently, a second copy of a gene encoding proclavaminate amidinohydrolase (pah1), an enzyme involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus, was identified and isolated. Using Southern analysis, we have now isolated second copies of th...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Tahlan, Kapil, Park, Hyeon Ung, Wong, Annie, Beatty, Perrin H., Jensen, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.930-939.2004
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